Looking for the best long-lasting ant killers to keep your home pest-free? We’ve tested and compared top brands like Ortho, Raid, and ant bait stations to bring you 10 reliable solutions in sprays, powders, and bait traps that work for months.
Ants can be a persistent problem in any home, but finding the right long-lasting ant killer can make all the difference. Our guide highlights the best products that keep ants away for months, not just days.
We’ve tested and compared top brands like Ortho, Raid, and ant bait stations to bring you reliable solutions. Whether you prefer sprays, powders, or bait traps, we’ve got you covered.
List of Top 10 Long Lasting Ant Killers
| Image | Title | Best For | Price |
|---|---|---|---|
 |
Ortho Orthene Ant and Roach Killer – Provides Long-Lasting Insect Control, Bug Killer for Indoor and Outdoor Use, 1 lb. |
Ortho Orthene Ant and Roach Killer is perfect for anyone who wants long-lasting bug control inside and outside their home. It’s easy to use and works on ants, roaches, fleas, and more. |
|
 |
Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand – Ready-To-Use Bug Spray, Kills Ants, Cockroaches & Spiders, 1.33 gal. |
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s great for families, pet owners, or anyone dealing with ants, roaches, or spiders. |
|
 |
48 PCS Ant Killer Gel Bait Stations, Extra Strengthen Ant Bait Traps, Long-Lasting Effective Pest Gel for Carpenter Ants and Other Common Household Ants, No Mess Easy Use, Safe for Pets and Kids |
Families with pets and kids that want a fast, no‑spray ant fix use these safe gel bait stations to stop ants inside and outside. |
|
 |
Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand – Ready-To-Use Home Bug Spray, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal. |
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s easy to use and works for a full year. |
|
 |
Raid Ant & Roach Killer, Fragrance Free Bug Killer for Home Use, Kills Bugs on Contact, 17.5 Oz, 2 Count |
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s easy to use and works fast to kill bugs on contact. |
|
 |
Ortho Home Defense Insect Killer for Cracks & Crevices – Bug Killer Spray Foam Kills Ants, Cockroaches, Fleas, Centipedes, Crickets, Boxelder Bugs & Other Listed Insects, Long-Lasting, 16 oz. |
This bug spray is perfect for anyone who wants to keep their home pest-free. It’s easy to use and works great in hard-to-reach spots. |
|
 |
Raid MAX Perimeter Protection Ant & Roach Killer Spray, Prevents Bugs by Killing for Up to 18 Months, Indoor and Outdoor Use, 22oz |
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s great for indoor and outdoor use, and it kills bugs for up to 18 months. |
|
 |
Ortho Home Defense Max Indoor Insect Barrier Battery-Powered Sprayer – Ready-To-Use Indoor Bug Spray, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1.5 L |
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s easy to use and works for a full year. |
|
 |
64 PCS Ant Killer Gel Bait Stations, Extra Strengthen Ant Bait Traps, Long-Lasting Effective Pest Gel for Carpenter Ants and Other Common Household Ants, No Mess Easy Use, Safe for Pets and Kids |
This ant killer gel bait is perfect for anyone who wants a fast, easy, and safe way to get rid of ants. It’s great for homes with kids and pets and works indoors and outdoors. |
|
 |
Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2 – Ready-To-Use Bug Spray Refill, Kills Ants, Roaches, and Spiders, 1 gal. |
This bug spray is perfect for anyone who wants to keep their home pest-free. It’s great for indoor and outdoor use, protecting against ants, roaches, spiders, and more. |
Detailed Reviews
Discover the top 10 long-lasting ant killers in our expert-reviewed guide. Each product is chosen for its powerful performance and great value. Whether you need indoor or outdoor protection, we’ve got you covered. Find the perfect solution to keep your home ant-free and enjoy peace of mind.
1. Ortho Orthene Ant and Roach Killer – Provides Long-Lasting Insect Control, Bug Killer for Indoor and Outdoor Use, 1 lb.
Ortho Orthene Ant and Roach Killer is a powerful insect control solution. It kills many pests, like ants, roaches, and spiders.
This odorless powder is easy to use. It works indoors and outdoors. It lasts up to 8 months.
Use it in cracks and crevices inside. Apply it around your home outside. Always follow the label for best results.
| Pros | Cons |
|---|---|
|
|
Perfect For:
Ortho Orthene Ant and Roach Killer is perfect for anyone who wants long-lasting bug control inside and outside their home. It’s easy to use and works on ants, roaches, fleas, and more.
Ready to Purchase?
2. Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand – Ready-To-Use Bug Spray, Kills Ants, Cockroaches & Spiders, 1.33 gal.
Ortho Home Defense Insect Killer is a ready-to-use spray that keeps bugs away. It works both inside and outside your home. Use it in kitchens, bathrooms, and around doors.
This spray kills ants, roaches, spiders, and more. It provides up to 12 months of protection indoors. The Comfort Wand makes spraying easy and continuous.
Apply it anytime as a preventative or when you see bugs. It’s safe for non-porous surfaces and long-lasting. Keep your home bug-free with Ortho.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s great for families, pet owners, or anyone dealing with ants, roaches, or spiders.
Ready to Purchase?
3. 48 PCS Ant Killer Gel Bait Stations, Extra Strengthen Ant Bait Traps, Long-Lasting Effective Pest Gel for Carpenter Ants and Other Common Household Ants, No Mess Easy Use, Safe for Pets and Kids
Say goodbye to ants with our 48 PCS Ant Killer Gel Bait Stations. This extra-strength formula targets carpenter ants, sugar ants, and more. It’s safe for pets and kids when used properly.
Place the bait stations indoors or outdoors, and let the long-lasting gel do the work. No mess, no fuss—just effective ant control for your home.
| Pros | Cons |
|---|---|
|
|
Perfect For:
Families with pets and kids that want a fast, no‑spray ant fix use these safe gel bait stations to stop ants inside and outside.
Ready to Purchase?
4. Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand – Ready-To-Use Home Bug Spray, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.
Ortho Home Defense Max keeps bugs away from your home. It kills ants, roaches, spiders, fleas, and ticks. This ready-to-use spray is easy to apply.
Use the Extended Reach Comfort Wand to spray without bending. It works indoors and outdoors for long-lasting protection.
Apply in kitchens, bathrooms, and basements. Use it anytime to prevent bugs or after seeing them.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s easy to use and works for a full year.
Ready to Purchase?
5. Raid Ant & Roach Killer, Fragrance Free Bug Killer for Home Use, Kills Bugs on Contact, 17.5 Oz, 2 Count
Raid Ant & Roach Killer is a powerful bug spray for your home. It kills bugs fast and keeps them away for up to 13 weeks.
This fragrance-free spray works on ants, roaches, spiders, and more. It’s easy to use and leaves no chemical smell behind.
Kills on contact. Lasts for weeks. Safe for home use.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s easy to use and works fast to kill bugs on contact.
Ready to Purchase?
6. Ortho Home Defense Insect Killer for Cracks & Crevices – Bug Killer Spray Foam Kills Ants, Cockroaches, Fleas, Centipedes, Crickets, Boxelder Bugs & Other Listed Insects, Long-Lasting, 16 oz.
Ortho Home Defense Insect Killer is a powerful foam spray that targets ants, cockroaches, and other pests. It’s designed to reach hidden cracks and crevices where bugs hide.
This spray offers long-lasting control, killing pests for up to 18 months on some surfaces. It’s safe for indoor and outdoor use and won’t stain surfaces.
The deep-penetrating foam spreads easily, creating an invisible protective barrier. It’s easy to use and works on hard-to-reach areas.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home pest-free. It’s easy to use and works great in hard-to-reach spots.
Ready to Purchase?
7. Raid MAX Perimeter Protection Ant & Roach Killer Spray, Prevents Bugs by Killing for Up to 18 Months, Indoor and Outdoor Use, 22oz
Raid MAX Perimeter Protection kills bugs and stops them from coming back. It works indoors and outdoors for up to 18 months. The spray is easy to use and reaches hidden spots.
It kills over 15 types of insects without leaving smells or stains. A refill option is also available for long-term use.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s great for indoor and outdoor use, and it kills bugs for up to 18 months.
Ready to Purchase?
8. Ortho Home Defense Max Indoor Insect Barrier Battery-Powered Sprayer – Ready-To-Use Indoor Bug Spray, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1.5 L
Ortho Home Defense Max keeps bugs out of your home for a full year. It’s ready to use right out of the box. The battery-powered sprayer makes it easy to apply.
Use it indoors in kitchens, bathrooms, and basements. Spray around doors and windows to block bugs from entering.
Apply it anytime to prevent bugs or stop infestations. It kills ants, roaches, spiders, fleas, and ticks fast.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home bug-free. It’s easy to use and works for a full year.
Ready to Purchase?
9. 64 PCS Ant Killer Gel Bait Stations, Extra Strengthen Ant Bait Traps, Long-Lasting Effective Pest Gel for Carpenter Ants and Other Common Household Ants, No Mess Easy Use, Safe for Pets and Kids
Say goodbye to ants with our 64 PCS Ant Killer Gel Bait Stations. This extra-strength formula targets all common household ants, including carpenter ants and fire ants.
Safe for kids and pets, these bait stations work indoors and outdoors. The mess-free design keeps the gel contained, making it easy to use anywhere.
Just place and forget—no spraying or cleanup needed. The long-lasting formula starts working fast, eliminating entire colonies in days. Protect your home with this 64-station value pack.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This ant killer gel bait is perfect for anyone who wants a fast, easy, and safe way to get rid of ants. It’s great for homes with kids and pets and works indoors and outdoors.
Ready to Purchase?
10. Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2 – Ready-To-Use Bug Spray Refill, Kills Ants, Roaches, and Spiders, 1 gal.
Ortho Home Defense Insect Killer is a ready-to-use bug spray that kills ants, roaches, spiders, and more. It works indoors and outdoors to keep pests away.
Use it anytime to prevent bugs or treat infestations. It lasts up to 12 months on non-porous surfaces. The 1-gallon refill lets you reuse your Comfort Wand.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This bug spray is perfect for anyone who wants to keep their home pest-free. It’s great for indoor and outdoor use, protecting against ants, roaches, spiders, and more.
Ready to Purchase?
Buying Guide
Ants can ruin your home’s peace. Finding the right ant killer keeps them away for months, not days. Our guide makes choosing easy and smart.
Factors to Consider When Buying Long-Lasting Ant Killers:
- Type of Product: Choose between sprays, powders, or bait stations. Sprays work fast, powders last long, and bait stations target colonies.
- Indoor vs. Outdoor Use: Pick a product that works where you need it. Some are for inside, others for outside, and a few do both.
- Safety: Look for pet-safe and kid-safe options. Always check the label for warnings.
- Duration of Protection: Go for products that last months, not weeks. Some offer up to 18 months of protection.
- Ease of Use: Ready-to-use sprays and bait stations are hassle-free. Powders may need careful application.
- Targeted Pests: Ensure the product kills ants and other pests like roaches or spiders if needed.
- Odor and Mess: Choose odorless or fragrance-free options. Avoid messy products for clean results.
- Brand Reliability: Trust top brands like Ortho and Raid for proven results.
Engaging Experience:
Say goodbye to ants with long-lasting solutions. Whether you prefer sprays, powders, or bait traps, our guide helps you find the best fit. Keep your home ant-free and enjoy peace of mind.